Summary The Senior Computational Scientist will participate in the collaborative bioinformatics program aligned with institutional strategy and direction and make leading contributions to the cutting edge projects at The Jackson Laboratory. They will closely work with the research faculty & staff across all three campuses of The JAX on projects of wide ranging complexity from a diverse array of biomedical disciplines such as cancer biology, ageing, immunology, infectious diseases, metabolomics, neural disorders, muscular disorders, Biostatistics & Statistical Genetics, and stem cell & developmental biology. They also work with research staff and services to meet the analytical needs of The JAX’s Services, clients and partners. In addition, will participate in all departmental activities and collaborations as assigned by their supervisor. They include but are not limited to, mentoring/supervising interns and scientists, post-doctoral fellows, scientists and grant writing. Successful candidates will have in-depth knowledge and experience in scientific areas such as High Throughput Sequence (HTS) data analysis (DNA Seq, mRNA Seq, ChIP Seq, micro RNA Seq etc), microarray data analysis, experimental design, data integration, algorithm development, development of sequence analysis tools (bioinformatics programming), evaluation of analytical tools and technology, and delivering training to the research community. They are continuous learners and proactive contributors. Furthermore, they will present the results to The JAX community, at conferences and workshops. A Senior Computational Scientist exhibits highest level of ability to work independently, development of in-depth knowledge in selected biological disciplines to analyze and provide expert reasoning to the relevant projects. They are expected to independently establish collaborations within The JAX provide expert reasoning to the projects relevant to the disciplines, contribute to grant writing in conjunction with the researchers at The JAX. To provide Leadership in grant applications as Co-I or bioinformatics leadership in a significant scientific program at The JAX. Provide overall project leadership that includes, not limited to, project management, logistics management, scope definition and collaboration management. A Senior Computational Scientist is expected to lead the collaborations, develop collaborative programs, to be a lead investigator in the grant applications and secure funding, and mentor junior scientists. Responsibilities Carries out Computational analysis of omics data, algorithm implementation as well as bioinformatics programming and expert reasoning and leadership for the projects. Evaluates data, for quality assurance and mining bioinformatics databases and contributes to the presentation of the results at conferences, workshops, and contributes to the preparation of manuscripts. Independently establishes collaborations within The Jackson Laboratory and provides expert reasoning to the projects relevant to the scientist’s disciplines of research, lead or co-lead grant writing consistently in collaboration with the researchers at The JAX as demonstrated by role as PI and co-I in the grant applications. Participates in departmental and project activities such as developing pipelines, participating in conducting courses and workshops at JAX, provide leading contributions to grant applications, mentoring students and scientists, and presenting results & processes to JAX community and at conferences and workshops as assigned. Demonstrates strong potential to carrying out the collaborative bioinformatics program independently. Mentor junior scientists, secure funds for the scientist’s group through independent collaborative research program and assist their manager in policy making. Sustain collaborations with The JAX research staff and faculty on both the Farmington, CT and Bar Harbor, ME campuses and to visit the other sites of JAX on a regular basis and as required. Qualifications PhD in Computer Science, Computatioanl Biology or related field. 7-12 years of experience in Bioinformatics research, excluding time spent to obtain PhD. Candidates with significant pre-doctoral experience in the relevant research area as a researcher and demonstrated research track record during the pre-doctoral period will also be considered. Demonstrated ability to establish research and mentoring leadership in addition to lead obtaining grant funds to support part of the group led by the Senior Computational Scientist. Successful incumbents demonstrate excellent verbal and written communication skills. Demonstrated experience managing projects and collaborations. Prior successes in and desire to contribute to team projects on an ongoing basis is a must. Proven track record of “omics data analysis, statistical genetics & Biostatistics, independent collaborative work and leading contributions to a biological discipline would be preferred. About Us The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,200 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center, a genomic medicine institute in Farmington, Conn., and facilities in Ellsworth, Maine, Sacramento, Calif., and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup. JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports. JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia in the United States in a poll conducted by The Scientist magazine! Our Values: INTEGRITY - Courage and commitment to do what is right PEOPLE - Inspiring our people to enhance the health of all ONE TEAM - Unified by our promise to transform medicine and science EXCELLENCE - Achieving world-class results INNOVATION - Leading with discovery and creative solutions STEWARDSHIP - Caring for and enhancing the resources entrusted to us What do we have to offer? JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria. Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health. The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws. Learn more about career opportunities at JAX: http://www.jax.org/careers.