Computational Biologist, Therapeutic R&D - Metabolism

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way?

 

What this position is all about:

Are you a highly motivated and organized computational biologist who is enthusiastic about developing, learning, and applying your computational skills to understand complex biological systems and disease?

You will get the opportunity to work in an innovative computational team, driven to deliver high-impact results. You will be in an early group of pioneers developing the world's first AI platform that unveils the causes of emergent disease based on cellular understanding.

You will begin your career at Cellarity with a slew of world-class computational biologists and machine learning scientists (https://cellarity.com/the-team), biologists (co-developing hypotheses), chemists, clinicians, and technologists (co-developing proprietary data assets).

If you think you can contribute to any of these aspects/capabilities that we are building and are keen on testing your hypotheses and learning from some of the best scientists, whilst getting to work with proprietary and relevant data sets, then we are looking for you.

 What you would be responsible for:

• Develop and apply computational biology and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets, with a focus on large-scale scRNA-seq & snRNA-seq disease atlases.
• Develop data analysis strategies and lead computational analyses on diverse biological and clinically relevant projects within metabolic diseases.
• Collaborate closely with experimental scientists and ensure that data is interrogated to deliver high value readouts.
• Contribute to experimental study designs that allow to measure what we predict.
• Present your results in an interdisciplinary team of biologists, chemists, clinicians, technologists, and other machine learning colleagues in meetings varying covering cross-functional project teams, functional teams, to whole company and management meetings.

 What experiences will you need:

• Ph.D. in biology, computational biology, or related scientific field.
• Minimum of 1 year relevant post graduate experience within academia and/or industry.
• Extensive experience in processing and analyzing single-cell transcriptomic data.
• Demonstrated scientific understanding of molecular and systems biology, diverse molecular data types, and analysis tools.
• Practical programming and scripting skills, preferably in Python.
• Fast learner, analytical thinker, creative, "hands-on", strong communication skills.
• Able to work both independently and as part of a team.

 What sets you apart:

• Experience driving an impactful and relevant project within industry.
• Experience in metabolic or liver diseases.
• Experience with generating, analyzing, and deriving hypotheses from large-scale single-cell atlases.
• Experience with clinical or biological data.
• Experience with emergent behavior in complex systems, time series analysis, transfer learning, multi-modal deep learning, geometric deep learning (learning on graphs and/or manifolds)
• Interested in learning any of the above

 What it is like to work at Cellarity
At Cellarity, we

1. Push Boundaries: We create a legacy with breakthrough science in the service of patients
2. Act with urgency: We work quickly and with conviction, and are eager to learn from data to iterate
3. Own it:  We transcend our job descriptions and relentlessly follow through on our commitments
4. Tell it like it is: We give regular feedback on behaviors and are accountable for how we treat people
5. Energize others: We are easy to work with and build strength from differing perspectives

Company Summary: 

Cellarity’s mission is to fundamentally redesign the way drugs are created for the sake of bringing new hope to patients.  By shifting the focus from a single target to the underlying cellular dysfunction, we unravel the complexity of disease biology and create medicines that were not possible before. The company has developed unique capabilities that link biology and chemistry with high dimensional -omics data from which we design medicines against the cellular signature of disease. The Cellarity platform allows us to uncover new biology in diseases even in the absence of known causal targets. The company has drug discovery programs underway in several disease areas, including metabolic disease, hematology, and immunology.  Cellarity recently completed a Series C financing and has raised a total of $274M from all funding rounds to date, with contributions from world-renowned investors alongside Flagship Pioneering who created the company.  Cellarity’s goal is to grow into a fully integrated next generation Biotech company driving a new age in drug creation.

 

Cellarity is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Cellarity does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Cellarity or its employees is prohibited unless contacted directly by Cellarity’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Cellarity, and Cellarity will not owe any referral or other fees with respect thereto.