Senior Bioinformatician
- Salary within the range of £34,000 - £40,000 per annum (depending upon experience)
- Job Ref: MI/24/10
- Duration of post: Fixed term until 31st March 2027
About the Role:
The goal of the CRUK National Biomarker Centre (NBC), is to develop, validate, and implement biomarkers that facilitate the optimisation of cancer patient treatment. In this regard, the NBC is an acknowledged world leader in the study of minimally invasive biomarkers, or liquid biopsies, for improving cancer management. Our biomarker research integrates clinical, molecular and computational science into a highly convergent programme. Advanced computational biology is critical to the biomarker agenda.
An exciting opportunity has arisen for a Bioinformatician to join the NBC. You will work alongside a multidisciplinary team of clinicians, biologists, engineers, and computational scientists to analyse genomic, epigenomic and transcriptomic data arising from patient blood samples; including cfDNA, cfRNA and circulating tumour cells. The primary focus will be to develop and apply a wide range of computational tools to sequencing data from liquid biopsy to develop and validate novel biomarkers that help better characterise patient tumours.
About You:
You will have a Degree in computational biology/bioinformatics, or related discipline (or equivalent relevant experience) plus significant data analysis experience. Alternatively, you will have a postgraduate degree related to cancer biology with demonstrable data analysis experience.
You will have relevant experience in data analysis (preferably with R/Bioconductor and/or Python), be able to work comfortably on the Linux command line and have a grasp of the statistical approaches used to analyse genome-wide datasets. An understanding of liquid biopsies, cancer genomics, and/or cancer biology are desirable, as is an understanding of bioinformatics pipelines (e.g. Nextflow). You will have strong communication skills and a desire to work collaboratively with scientists from other disciplines. Experience of multidisciplinary teamwork would be beneficial.
This role would be suitable for a specialist in data analysis wishing to expand upon their cancer related knowledge, or a cancer bench scientist transitioning into a career in computational analysis.
Why choose the CRUK Cancer Biomarker Centre?
We are an internationally leading biomarker centre aligned to the world leading Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), The Biomarker Centre and Manchester Institute are core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world.
The Cancer Biomarker Centre is located in the New Paterson Building, a £150 million flagship purpose-built biomedical research facility directly attached to The Christie NHS Foundation Trust in South Manchester. Situated on the third floor, the Cancer Biomarker Centre offers world-class research facilities with bespoke, purpose-built suite of laboratories in close proximity to discovery science collaborators and the Christie Hospital’s clinical trialists.
Our Centre’s aim is to discover, develop, validate and qualify biomarkers that support optimised treatment of patients with cancer. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to translational research and biomarker driven clinical trials.
How to apply?
To apply for this position please complete the online application via ‘https://www.cruk.manchester.ac.uk/recruitment/candidate/searchvacancies’. Please ensure you detail the names of two referees and ensure you submit your application before the closing date specified.
Please note this vacancy will close for applications at 11:59pm on the closing date specified.
What you will get in return:
- Fantastic market leading Pension scheme
- Excellent employee health and wellbeing services including an Employee Assistance Programme
- Exceptional starting annual leave entitlement, plus bank holidays
- Additional paid closure over the Christmas period
- Local and national discounts at a range of major retailers
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Our University is positive about flexible working – you can find out more here
Hybrid working arrangements may be considered.
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk.
Any CV’s submitted by a recruitment agency will be considered a gift.
Enquiries about the vacancy, shortlisting and interviews:
Dr Florent Mouliere: florent.mouliere@cruk.manchester.ac.uk
Dr Alex Clipson: alexandra.clipson@cruk.manchester.ac.uk
Dr Steven Hill: steven.hill@cruk.manchester.ac.uk
General enquiries:
Email: People.recruitment@manchester.ac.uk
Technical support:
https://jobseekersupport.jobtrain.co.uk/support/home
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.
