Research Prime

Senior Scientist, Translational Bioinformatics

Organisation Name: Bristol Myers Squibb
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Country: Spain

Job Description:

Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Senior Scientist Translational Bioinformatics CITRE-based CITRE based in Seville Spain is Bristol Myers Squibbs research institute in Europe and our link to the European research community. At IPS (Informatics & Predictive Sciences) we perform innovative computational research to inform decisions across all stages of drug development. Areas of research include computational and network biology machine/deep learning cheminformatics predictive modeling patient stratification and method development for analysis and interpretation of biological data. We seek a computational biologist to fill a job position as Senior Scientist Translational Bioinformatics. The successful candidate will join a broad and cross-functional scientific community at the leading-edge of therapeutic innovation to serve as a central node in our precision discovery efforts. The position requires a multi-disciplinary profile with advanced computational skills rooted in in-depth knowledge of disease biology (oncological diseases) and driven by a strong motivation to transform the lives of cancer patients. Main goal is dissecting molecular complexity to gain a better understanding of disease heterogeneity informing highly precise drug development. Are you up for the challenge? Analytic work will focus on exploratory analysis of multi-omics (data types including WGS WES and bulk/sc/st-RNA-seq) and clinical data from both patients and ex-vivo models. This involves predictive modelling (including statistical methods and modern data science techniques) advanced visualizations and delivery of impactful data packages to stakeholders in the research organization among other specific tasks. In addition to the internal duties the successful candidate will engage with the external scientific community through collaborations scientific articles communications to congresses etc. The position would suit an individual with strong biological and computational capabilities together with excellent resourcefulness communication and collaboration skills. Applications are encouraged from candidates involved in innovative translational research in oncology at a clinical academic or industrial research settings. Responsibilities Apply computational methods for patient stratification based on integration of multi-omic datasets. Drive in-depth analysis of stratified patient data to elucidate biological and driver mechanisms in key oncology indications. Contribute to developing classifiers based on molecular data to validate patient segments in clinical cohorts. Contribute to the identification of ex-vivo models and validation scenarios to accurately represent key disease subtypes in experimental settings. Work with colleagues in the Informatics & Predictive Sciences group to identify drivers of disease heterogeneity and potential therapeutic targets for patients in unmet need. Collaborate with experimental teams in the iterative validation of therapeutic and mechanistic hypotheses. Summarize analysis results and report conclusions to BMS decision-making bodies. Qualifications PhD with 2+ or MS with 4+ years of experience in computational biology bioinformatics statistics or related fields. Experience in biotech or pharmaceutical industries is a plus. Strong experience in the use of a high-level programming language such as R MATLAB Python Perl for complex data analysis and reproducible research practices. Good understanding of disease biology and molecular mechanisms in oncology. Experience working with Next Generation Sequencing datasets including Whole-Genome Whole-Exome Sequencing and RNA-seq (bulk single-cell spatial transcriptomics). Familiarity with contemporary cloud and high-performance computing environments. Expertise in application of contemporary machine-learning/AI approaches is a plus. Ability to work both independently and collaboratively and to handle several concurrent fast-paced projects while conforming with rigorous requirements of clinical studies. Strong problem-solving and collaboration skills rigorous and creative thinking. Excellent communication data presentation and visualization skills. Fluent written and verbal English language communication. Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to gender identity race color religion sexual orientation national origin or disability. If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Posting Date: Jan 16, 2024
Closing Date:
Organisation Website/Careers Page: https://careers.bms.com/jobs/R1577328?lang=en-us


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