Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. At Bristol Myers Squibb we are inspired by a single vision transforming patients lives through science. In oncology hematology immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contributes to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary We are looking for passionate graduate students who are seeking summer internship opportunities to learn grow and work alongside other talents. The Intern will work in Computational Genomics (CG) under the guidance of an experienced scientist. Through the application of innovative bioinformatics tools and methods CG is responsible for analyzing genomics NGS (Next Generation Sequencing) data sets generated from pre-clinical and clinical studies. These include RNA-Seq Exome and Whole Genome Sequencing. CG interacts with and influences all aspects of R&D (Research & Development) at BMS from early discovery through late-stage development. The internship will also provide an opportunity to gain an understanding of the drug development process through interactions with project teams and opportunity to network with individuals from multiple disciplines in BMS. The intern will have the opportunity to understand and contribute to various aspects of CG including NGS data analysis development of computational pipelines and assist in expanding the teams NGS capabilities. Key Responsibilities Work with an experienced scientist(s) in the Computational Genomics group on a project applicable to one or more of the following: Understanding the effect of genetic ancestry on various biomarkers generated from NGS data for e.g. Tumor Mutational Burden (TMB) and Microsatellite Instability (MSI). Understanding the effect of depth of sequencing coverage on Microsatellite Instability (MSI) scores generated from NGS data. Productionizing a pipeline for analyzing high-throughput low-cost RNA-Seq data generated from plate-based assays utilizing sample barcodes and Unique Molecular Identifiers (UMIs). Assist in comparing tools developing and productionizing a pipeline for the identification of known and novel splice junctions/alternative transcript isoform events from RNA-Seq data. Compare NGS pipelines to optimize workflows used to support clinical trials. Tasks may include: Establish prototype of proposed analysis to prove effectiveness. Apply pipeline to existing clinical trial data to explore results that could potentially impact downstream analysis. Identify potential QC (Quality Control) issues and limitations with using this framework. Communicate problems findings and methods with other scientists throughout this process. Qualifications & Experience Senior B.S. M.S. or Ph.D. graduate student in Bioinformatics Computer Science or related field no work experience required. Fluency with Linux-based high-performance computing environments including python Linux shell scripting R ssh and git. Experience with DNA-Seq and RNA-Seq pipelines and data a plus. Experience with pipeline development and deployment via slurm Common Workflow Language (CWL) a plus. Some hands-on experience with common NGS tools (GATK Picard etc.) a plus. Strong problem-solving and collaboration skills and rigorous and creative thinking. Excellent written and oral communication skills including an ability to explain complex ideas to computational scientists experimentalists and clinicians. The ability to collaborate with diverse groups across the organization and solve problems that will benefit downstream analysts and decision-making teams. Why You Should Apply Around the world we are passionate about impacting the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. BMSEC BMSINTERN BMSCO-OP If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
