Faculty of Health and Medical Sciences
University of Copenhagen
We are looking for a highly motivated and dynamic postdoc for a 23 month position starting Jan 1st 2024 to work on the design and characterization of de novo microproteins for therapeutic applications. This is a DFF (Danmarks Frie Forskningsfond) funded position.
Information on the department can be found at: https://ilf.ku.dk/
Our research
The Rogers lab is working to find valuable new molecules: new in form function or both. We are particularly interested in exploring biopharmaceuticals modified peptides and proteins as next-generation therapeutics. This requires international collaboration and working at the intersection of molecular biology protein science organic chemistry biophysics and chemical biology.
Your job
The emergence of deep learning-based methods is revolutionizing protein design. Small stable microproteins can now be generated routinely and reliably and these can be imbued with functions such as binding to particular protein targets. Your tasks will be to apply the newest design methods to discover new binders filter hits order DNA constructs for expression screen initial hits express and purify the best designs and fully characterize binding biophysics to reveal their therapeutic potential.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
- You have a PhD in chemistry biochemistry biology chemical biology or pharmacology
- You are highly experienced in molecular biology protein expression and purification biophysics of molecular interactions (e.g. SPR BLI ITC circular dischorism DSF).
- You have an active interest in new drug modalities
- Proficient communication skills and ability to work in teams
- Excellent English skills written and spoken
Desirable experience and skills:
- Knowledge of deep learning methods applied to protein design.
Place of employment
The place of employment is at the Department of Drug Design and Pharmacology University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories facilities for protein expression and purification computational resources protein NMR state-of-the-art biophysical equipment and analysis.
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of 23 months. The starting date is Jan 1st 2024.
Salary pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently the monthly salary starts at 36400 DKK/approx. 4880 EUR (October 2023 level). Depending on qualifications a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information please contact joseph.rogers@sund.ku.dk +45 23 84 00 87; www.sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking Apply now below. Furthermore your application must include the following documents/attachments all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education work/research experience language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed a written statement from the supervisor will do.
- List of publications.
Deadline for applications: 19 October 23.59pm CET
We reserve the right not to consider material received after the deadline and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
Interviews are expected to be held in November 2023
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
