Research Prime

Senior Scientist, Machine Learning

Organisation Name: Bristol Myers Squibb
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Country: United States

Job Description:

Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. When you join BMS you are joining a diverse high-achieving team united by a common mission. The Informatics and Predictive Sciences (IPS) mission is to Pioneer Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic structural and molecular informatics computational and systems biology patient selection and translational biomarker research and broader fields including knowledge science epidemiology and machine learningacross the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field both inside and outside the company. We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so our work transforms the lives of patients as well as our own lives and careers. Here youll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. Youll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. We seek a collaborative and highly innovative computational scientist to join our Predictive Sciences team and develop predictive models using cutting-edge machine learning/artificial intelligence techniques to discover novel therapeutic opportunities. This position will work alongside colleagues in Informatics & Predictive Sciences (IPS) Protein Homeostasis Small Molecule Drug Design and other teams in BMS Research and play a key scientific role in shaping the future of our most advanced therapeutic approaches primarily focusing on protein degradation to pursue opportunities beyond the reach of conventional small molecules. We welcome applications from candidates who are passionate about learning new drug discovery paradigms bringing new medicines to the patients and comfortable working in a fast-paced and highly collaborative environment. Responsibilities: Interrogate properties of protein-protein and protein-ligand interaction surfaces and their molecular representations. Develop and apply state-of-the-art artificial intelligence/machine learning algorithms including geometric deep learning and graph-based models to predict complex biomolecular interactions and their selectivity. Devise AI/ML strategy to predict or de novo design small molecule ligands that enhance complex protein-protein interaction interfaces. Design experiments to elucidate protein interactions at the molecular level process and analyze data for model training or to validate findings. Communicate results and findings to scientific project teams and stakeholders. Contribute to planning and execution of collaborative projects with leading academic and commercial research groups worldwide. Basic Qualifications: Bachelor's Degree in computer science bioinformatics machine learning or computational biology and 7+ years of academic / industry experience or Master's Degree in computer science bioinformatics machine learning or computational biology and 5+ years of academic / industry experience or PhD in computer science bioinformatics machine learning or computational biology 2+ years of academic / industry experience Preferred Qualifications: Ph.D. in machine learning with 2+ years of post-doctoral experience in applying computational and analytical approaches in university pharma or biotech settings. Expertise in developing state-of-the-art deep learning techniques including diffusion models and large language models. Experience with deep learning frameworks such as PyTorch TensorFlow Keras including underlying implementations. Demonstrated ability to design & engineer multiple molecular representations and apply predictive multivariate research approaches to integrated molecular and chemistry datasets. Strong working knowledge of protein structure/folding and protein-ligand interaction prediction. Strong problem-solving skills and ability to work independently and as part of a team. Excellent communication and interpersonal skills. The starting compensation for this job is a range from $109000 to $150700 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job such as required skills and where the job is performed. Final individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit our BMS Career Site. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program. If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Posting Date: Sep 21, 2023
Closing Date:
Organisation Website/Careers Page: https://careers.bms.com/jobs/R1573045?lang=en-us


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