Principal Software Engineer, Computational Genomics
Organisation Name: Bristol Myers Squibb
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Country: United States
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Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. This role can be fully Remote When you join BMS you are joining a diverse high-achieving team united by a common mission. The Informatics and Predictive Sciences (IPS) mission is to Pioneer Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic structural and molecular informatics computational and systems biology patient selection and translational biomarker research and broader fields including knowledge science epidemiology and machine learningacross the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field both inside and outside the company. We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so our work transforms the lives of patients as well as our own lives and careers. Here youll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. Youll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. We are seeking a principal software engineer to help advance our NGS data management and analysis platform. This role serves as a key member of the group to develop & maintain our NGS platform as well as help enable our scientists with new genomic data analysis capabilities. Expertise in the software development lifecycle Python/Flask framework front-end UI/UX Amazon Web Services are prerequisite. Experience or knowledge in processing analyzing integrating and visualizing NGS data as well as creating CWL-based pipelines would be beneficial. The Computational Genomics group is made up of scientists and software developers who perform a combination of NGS data analysis and/or engineering to support both research projects and clinical trials. Our primary focus is to: Manage NGS data across the organization Process NGS data in support of research and clinical trials Integrate or develop new tools and analysis pipelines to support multiple therapeutic areas (including Immuno-Oncology Cardiovascular Fibrosis and Immunoscience) through the strategic application of cutting-edge bioinformatics approaches Develop integrate and support infrastructure to enable all the above Responsibilities Support and continue to develop platform used to facilitate data gathering ingestion and acquisition by various groups around the world. Support and continue to develop data integration services to help automate analysis of data on various platforms. Create automation systems and tools to configure monitor and orchestrate data infrastructure and pipelines. Support and continue to develop Web-based user interface for all of the above. Maintain ongoing reliability performance and support of both front-end and back-end infrastructure including providing solutions based on application needs and anticipated growth. Work closely with scientists and engineers within (and outside) the group to design develop and build integrated solutions for improved usability and serviceability. Stay current on modern software architectures for various use-cases. Contribute to documentation of software workflows and infrastructure. Mentor junior developers and review contributions to code base. Basic Qualifications: Bachelor's Degree and 8+ years of academic / industry experience (Computer Science Bioinformatics or similar field). or Master's Degree and 6+ years of academic / industry experience (Computer Science Bioinformatics or similar field). or PhD and 4+ years of academic / industry experience (Computer Science Bioinformatics or similar field). Preferred Qualifications B.S. with 8+ yrs. M.S. with 5+ yrs. or Ph.D. with 2+ yrs. of academic / industry experience (Computer Science Bioinformatics or similar field). Multiple years of experience building large complex distributed scalable software applications Experience using various modern front-end and back-end frameworks including Python Flask relational (Postgres MySQL Oracle) and NoSQL databases. Experience with AWS services including Elastic Beanstalk ECS/ECR AWS Batch CloudWatch. Skills Abilities and Competencies: Fluency with Linux-based high-performance computing environments including AWS Web Services (Elastic Beanstalk EC2 S3 CloudFormation Batch CloudWatch Lambda ECR) Docker Source Control systems Git conventions and CI/CD pipelines using Jenkins or GitHub Actions Writing front-end and back-end code to implement requirements along with unit and integration tests to ensure code works as expected Knowledge of UI/UX best practices Knowledge of Javascript and various web development frameworks. Strong detail-oriented problem-solving and collaboration skills and rigorous creative thinking Proven ability to work independently (with necessary guidance) self-motivated to learn and integrate new technologies manage multiple projects simultaneously keep accurate records/notes and comply with company policies Excellent written and oral communication skills including an ability to explain complex ideas to various groups of scientists and engineers Knowledge of CWL pipeline development and execution using open source tools a plus. Knowledge of commonly used NGS/Bioinformatics analysis tools such as samtools picard GATK and common file formats such as FASTQ VCF and BAM a plus The starting compensation for this job is a range from $121000 to $167200 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job such as required skills and where the job is performed. Final individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit our BMS Career Site. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program. #LI-Remote If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
