Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. The Division of Drug Product Development Materials Science & Engineering Group at Bristol Myers Squibb is seeking a highly motivated computational chemist with expertise in crystal structure prediction of small organic molecules molecular modeling and crystal structure design. This role will oversee efforts in Crystal Structure Prediction (CSP) for early development pharmaceutical candidates including working with external vendors and helping to support and standardize CSP as a key workflow within MSE. This role will also oversee efforts to provide in silico approaches to crystal engineering crystal structure design and co-crystal prediction and development. Responsibilities: Support Crystal Structure Prediction at Bristol Myers Squibb Plan scope of work for critical assets based on project needs and known solid state form space. Execute and/or oversee CSP studies on priority assets Provide energy rankings for known structures Suggest and design additional CSP studies for key forms Present results to project teams and assist in design of experiments to crystallize predicted forms. Work to develop new approaches to CSP which best meet challenges posed by specific BMS compounds Develop computational approaches for Crystal Engineering projects Utilize computational tools to provide understanding of relative stability of known crystalline forms provide assessment of relative stability of similar compounds based on known crystal structures Utilize CSP and other computational tools to assist with crystal structure design of novel forms Develop new tools to assist with co-crystal prediction workflows Assist with design of experiments to help produce new crystalline forms including solvent temperature pressure and other environmental or chemical variables. Requirements: PhD in Computational Chemistry or related field with 1-3 years relevant work experience in Crystal Structure Prediction. Experience with various computational chemistry software packages such as: QuantumESPRESSO VASP or similar Gaussian Psi4 Orca or similar Crystal TURBOMOLE or similar CHARMM LAMMPS OpenMM or similar Proficiency in Python scripting Experience in setting up executing and troubleshooting atomistic simulations on high performance computers. Desirable skills: Familiarity with the Cambridge Structural Database and related tools specifically the CSD Python API. Experience with cheminformatics tools such as RDkit Ability to work with in a project based highly coordinated environment If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
