Principal Scientist, Translational Bioinformatics Late Stage Immunology, Cardiovascular and Neurology
Organisation Name: Bristol Myers Squibb
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Country: United States
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Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. When you join BMS you are joining a diverse high-achieving team united by a common mission. The Informatics and Predictive Sciences (IPS) mission is to Pioneer Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic structural and molecular informatics computational and systems biology patient selection and translational biomarker research and broader fields including knowledge science epidemiology and machine learningacross the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field both inside and outside the company. We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so our work transforms the lives of patients as well as our own lives and careers. Here youll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. Youll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. We are seeking a highly motivated bioinformatician with discovery preclinical or clinical experience to join our Translational Bioinformatics Immunology Cardiovascular and Neurology (ICN) team within Informatics and Predictive Sciences group. The successful candidate will help advance Bristol Myers Squibbs industry leading ICN programs through the strategic application of cutting edge bioinformatics approaches. Responsibilities Analyze various -omic-scale data generated from human subjects in BMS clinical trials and other observational cohorts including RNA-Seq Exome and Whole Genome Sequencing high throughput proteomics and multiplex flow cytometry to build comprehensive understanding of diseases identify segments of patients with unmet medical needs form drug combination strategy and inform new targets prioritization. Generate testable and interpretable hypotheses from patient derived data sets to inform precision discovery programs. Maximize application of clinical data on research and early pipeline programs via reverse translation projects in close partnership with teams across Research and Development including bioinformaticians statisticians biologists biomarker leads and clinicians. Define and execute statistical/computational analysis plans. Participate in authorship of scientific reports and present methods and conclusions to publishable standards. Basic Qualifications: Bachelor's Degree in bioinformatics engineering statistics physics molecular biology genetics or a similar discipline and 8+ years of academic / industry experience or Master's Degree in bioinformatics engineering statistics physics molecular biology genetics or a similar discipline and 6+ years of academic / industry experience or PhD in bioinformatics engineering statistics physics molecular biology genetics or a similar discipline and 4+ years of academic / industry experience Preferred Qualifications: Ph.D. in bioinformatics engineering statistics physics molecular biology genetics or a similar discipline. Five (5) or more years relevant experience in preclinical or clinical research for principal scientist level Position can be filled at a different level based on depth of experience and scientific expertise Experience and expertise integrating large complex sparse non-oncology multi-modal data sets including germline genetics disease biopsies circulating biomarkers and reference single-cell -omics. Expertise in modern AI/ML methods to generate testable and interpretable hypothesis regarding causal disease biology and identification of homogeneous subsets of patients complex disorders Problem-solving and collaboration skills rigorous and creative thinking Ability to communicate effectively with biologists and computational scientists. Proficiency using high level programming languages (R and Bioconductor packages preferred) Background in immunoscience cardiovascular or neurological diseases preferred Proven track record of independent research under minimal supervision. The starting compensation for this job is a range from $121000 to $167200 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job such as required skills and where the job is performed. Final individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit our BMS Career Site. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program. #QLR If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
