About the Department
Dicerna, a Novo Nordisk company, is focused on driving
innovation in RNAi (ribonucleic acid interference) to
selectively target and silence genes that cause or contribute to
disease. Our proprietary GalXC™ and GalXC-Plus™ RNAi
technologies have the potential to address conditions that are
difficult or impossible to treat with other modalities.
Established as a Transformational Research Unit (TRU) following
Novo Nordisk’s acquisition of Dicerna Pharmaceuticals, Inc. in
December 2021, the Dicerna TRU is a unique new organization
within Novo Nordisk that brings together the best of both worlds
– the agility, collaborative pioneering spirit and calculated
risk-taking profile of a biotech along with the scale, resources
and capabilities of a global leader in drug development. With
approximately 200 researchers, scientists, drug developers and
operational staff, we are a team of inventive and
entrepreneurial thinkers pushing the boundaries of science to
create and drive new RNAi-based therapies for both rare and more
prevalent diseases from the bench to the clinic. Together, we
are driving change. Are you ready to make a difference?
The Position
We are seeking an experienced B.S./M.S. Computational
Biologist to help in our drug discovery efforts. This is a
hands-on, full-time, research position that requires strong
expertise in computational biology.
The Associate Computational Biologist, will provide hands-on
research-based support for RNAi-based drug discovery programs
that require strong expertise in computational biology. We are
looking for a highly motivated individual with strong
quantitative and computational background and experience in
genomics/transcriptomics (analysis of different bulk/single cell
next generation sequencing techniques as well as application of
novel methods). We welcome proof of experience such as links to
GitHub/Bitbucket pages, and relevant
bioinformatics/computational biology/machine learning community contributions.
Relationships
This position reports to the Scientist I, Computational
Biologist, Systems Biology
Essential Functions
- Perform the analysis, visualization, and interpretation of
large biological datasets (including but not limited to
RNA-seq data)
- Derive insights from internally generated and publicly
available next-generation sequencing (NGS) datasets and other
genomic data
- Contribute towards the maintenance and improvement of
Dicerna’s computational pipelines
- Work collaboratively in a cross-functional team
environment to provide conceptual input in experimental design
- Summarize, visualize, and communicate analyses and
findings to key stakeholders
- Generate technical reports, prepare presentation slides,
and improve existing analytic tools
- Maintain thorough written records of experiments and methods
Physical Requirements
0-10% overnight travel required.
Qualifications
- Bachelor's or Master's degree in Computational Biology,
Bioinformatics, Biostatistics, Systems Biology, Genetics,
Computer Science, or another quantitative field
- Good understanding of routine transcriptomics (RNA-seq,
scRNA-seq) data analysis workflows is preferred
- Proven programming skills in R and/or Python. Fluency in
C/C++ is a plus
- Hands-on experience with common bioinformatics tools (such
as genome browsers) and major public genomics databases
- Outstanding written and verbal communication skills
- Commitment to quality, attention to detail, and team
player mentality is a must
- Hands-on experience on the computational analysis and
interpretation of NGS datasets is preferred
- Experience with high-performance computing (HPC) or cloud
computing platform is a plus
- Wet-lab molecular biology and cell biology experience is a plus
- Experience with RNAi is a plus
We commit to an inclusive recruitment process and equality
of opportunity for all our job applicants.
At Novo Nordisk we recognize that it is no longer good
enough to aspire to be the best company in the world. We need to
aspire to be the best company for the world and we know that
this is only possible with talented employees with diverse
perspectives, backgrounds and cultures. We are therefore
committed to creating an inclusive culture that celebrates the
diversity of our employees, the patients we serve and
communities we operate in. Together, we’re life changing.
Novo Nordisk is an equal opportunity employer. Qualified
applicants will receive consideration for employment without
regard to race, ethnicity, color, religion, sex, gender
identity, sexual orientation, national origin, disability,
protected veteran status or any other characteristic protected
by local, state or federal laws, rules or regulations.
If you are interested in applying to Novo Nordisk and need
special assistance or an accommodation to apply, please call us
at 1-855-411-5290. This contact is for accommodation requests
only and cannot be used to inquire about the status of applications.