Research Prime

Associate Computational Biologist

Organisation Name: Novo Nordisk
Organisation Type:
City: Lexington
State:
Country: United States

Job Description:

About the Department

Dicerna, a Novo Nordisk company, is focused on driving innovation in RNAi (ribonucleic acid interference) to selectively target and silence genes that cause or contribute to disease. Our proprietary GalXC™ and GalXC-Plus™ RNAi technologies have the potential to address conditions that are difficult or impossible to treat with other modalities. Established as a Transformational Research Unit (TRU) following Novo Nordisk’s acquisition of Dicerna Pharmaceuticals, Inc. in December 2021, the Dicerna TRU is a unique new organization within Novo Nordisk that brings together the best of both worlds – the agility, collaborative pioneering spirit and calculated risk-taking profile of a biotech along with the scale, resources and capabilities of a global leader in drug development. With approximately 200 researchers, scientists, drug developers and operational staff, we are a team of inventive and entrepreneurial thinkers pushing the boundaries of science to create and drive new RNAi-based therapies for both rare and more prevalent diseases from the bench to the clinic. Together, we are driving change. Are you ready to make a difference?

 

The Position

We are seeking an experienced B.S./M.S. Computational Biologist to help in our drug discovery efforts. This is a hands-on, full-time, research position that requires strong expertise in computational biology.

 

The Associate Computational Biologist, will provide hands-on research-based support for RNAi-based drug discovery programs that require strong expertise in computational biology. We are looking for a highly motivated individual with strong quantitative and computational background and experience in genomics/transcriptomics (analysis of different bulk/single cell next generation sequencing techniques as well as application of novel methods). We welcome proof of experience such as links to GitHub/Bitbucket pages, and relevant bioinformatics/computational biology/machine learning community contributions.

 

Relationships

This position reports to the Scientist I, Computational Biologist, Systems Biology

 

Essential Functions

  • Perform the analysis, visualization, and interpretation of large biological datasets (including but not limited to RNA-seq data)
  • Derive insights from internally generated and publicly available next-generation sequencing (NGS) datasets and other genomic data
  • Contribute towards the maintenance and improvement of Dicerna’s computational pipelines
  • Work collaboratively in a cross-functional team environment to provide conceptual input in experimental design
  • Summarize, visualize, and communicate analyses and findings to key stakeholders
  • Generate technical reports, prepare presentation slides, and improve existing analytic tools
  • Maintain thorough written records of experiments and methods

 

Physical Requirements

0-10% overnight travel required.

 

Qualifications

  • Bachelor's or Master's degree in Computational Biology, Bioinformatics, Biostatistics, Systems Biology, Genetics, Computer Science, or another quantitative field
  • Good understanding of routine transcriptomics (RNA-seq, scRNA-seq) data analysis workflows is preferred
  • Proven programming skills in R and/or Python. Fluency in C/C++ is a plus
  • Hands-on experience with common bioinformatics tools (such as genome browsers) and major public genomics databases
  • Outstanding written and verbal communication skills
  • Commitment to quality, attention to detail, and team player mentality is a must
  • Hands-on experience on the computational analysis and interpretation of NGS datasets is preferred
  • Experience with high-performance computing (HPC) or cloud computing platform is a plus
  • Wet-lab molecular biology and cell biology experience is a plus
  • Experience with RNAi is a plus

 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

 

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

 

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.


Posting Date: Jul 11, 2023
Closing Date:
Organisation Website/Careers Page: https://www.novonordisk.com/content/nncorp/global/en/careers/find-a-job/job-ad.281687.en_US.html


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