Associate Director Computational Biologics Sequence Discovery and Design, Predictive Sciences
Organisation Name: Bristol Myers Squibb
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Country: United States
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Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. When you join BMS you are joining a diverse high-achieving team united by a common mission. The Informatics and Predictive Sciences (IPS) mission is to Pioneer Partner and Predict to drive transformative insights for patient benefit. IPS conducts applied computational research in areas that include genomic structural and molecular informatics computational and systems biology patient selection and translational biomarker research and broader fields including knowledge science epidemiology and machine learningacross the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the field both inside and outside the company. We perform innovative science to empower key data-driven decisions across a rich pipeline of next-generation medicines. In doing so our work transforms the lives of patients as well as our own lives and careers. Here youll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. Youll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. JOB DESCRIPTION We are seeking a creative and collaborative scientist and technologist to lead a computational sequence identification team to help us discover and design novel biologics. You have expertise in building and scaling next-generation sequencing technologies pipelines and workflows that connect to machine learning and predictive models and integrate with automation and functional assays to drive closed-loop design of protein therapeutics with desired binding characteristics and biological activity. This role provides the opportunity to work on multidisciplinary teams to solve challenging problems in the discovery and design of new biologics. We are deeply passionate about what we do here at Bristol Myers Squibb because we know that our work helps deliver truly innovative and life-changing therapies for complex diseases of unmet medical need. If this inspires you as well were excited to have you join us! RESPONSIBILITIES Lead a high-functioning team focused on sequence identification and characterization of antibodies and related biologics in support of BMS pipeline of therapeutic programs Leverage automation data science bioinformatics and machine learning to expand the throughput of antibody screening platforms including data curation analysis and interpretation of large data sets Partner with project teams to build workflows and pipelines around analytical frameworks for antibody repertoire sequencing Present strategies approaches results and conclusions to a publishable standard in static and interactive formats Collaborate with discovery biotherapeutics teams to develop an integrated approach for identifying molecules with novel binding and functional properties to progress Coach mentor and develop talent Establish and strengthen the interface between teams including streamlining communication operations and data systems Participate in authorship of scientific reports and present methods and conclusions to publishable standards BASIC QUALIFICATIONS Bachelor's Degree in biochemistry biophysics computer science engineering or related field and12+ years of academic / industry experience or Master's Degree in biochemistry biophysics computer science engineering or related field and 10+ years of academic / industry experience or PhD in biochemistry biophysics computer science engineering or related field and 8+ years of academic / industry experience 4+ years of leadership experience PREFERRED QUALIFICATIONS PhD in biochemistry biophysics computer science engineering or related field with 10+ years of experience with half of that time being in biopharma or biotechnology industries. Candidates with BSc/MSc degrees and 15+ years of relevant biotech industry experience will also be considered. Demonstrated expertise in biotherapeutic sequencing technologies and characterization. Experience scaling workflows and processes that leverage high-throughput technologies. Deep understanding of binding kinetics affinity epitope and mechanism of action using surface plasmon resonance (SPR) or orthogonal technologies such as BLI ITC ELISA. In depth understanding of antibody sequence structure and antigen engagement. Excellent problem-solving skills and teamwork. Strong communication data presentation and visualization skills. A track record of successful people and team leadership with a focus on developing talent. Experience with laboratory information management systems (LIMS) is desired. The starting compensation for this job is a range from $179000 to $220000 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job such as required skills and where the job is performed. Final individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit our BMS Career Site. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program. #QLR If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
