Principal Scientist, Translational Bioinformatics, Informatics & Predictive Sciences
Organisation Name: Bristol Myers Squibb
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Country: United States
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Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Principal Scientist Translational Bioinformatics Informatics & Predictive Sciences We are seeking a talented and motivated computational scientist to join the Translational Bioinformatics team at Bristol Myers Squibb (BMS). This role will lead the analysis of multimodal datasets generated from novel technologies with BMS Translational Research and other collaborators across the organization. This scientist will be a critical contributor for Precision Discovery efforts to identify biomarker-defined patient segments and target hypotheses for the next generation of BMS assets. This position would suit an individual with strong computational and biological capabilities with a demonstrated track record of translating complex data into testable hypotheses. The Translational Bioinformatics group provides an exciting opportunity to collaborate with cross-functional teams across the R&D pipeline make major contributions to scientific knowledge of cancer disease biology and to directly impact treatment of cancer patients. Responsibilities Under the guidance of senior team members engage key stakeholders in BMS Translational Research and other teams across the organization to define and execute biomarker analysis plans on multimodal datasets from pre-clinical BMS clinical trial and real-world data cohorts. Develop computational methods for patient segmentation from molecular profiling datasets for various treatment modalities to inform oncology strategy. Perform analyses of data generated by cutting edge technologies (e.g. scRNAseq spatial transcriptomics high parametric flow and in-vitro immune function assays) Evaluate and apply machine learning (ML) and artificial intelligence (AI) methods to enable precision discovery efforts. Interrogate mechanisms of disease biology to accurately predict response or resistance to BMS therapies. Summarize analysis results and report conclusions to BMS decision-making bodies. Basic Qualifications: Bachelor's Degree in computational biology bioinformatics statistics or related fields and 8+ years of academic / industry experience or Master's Degree in computational biology bioinformatics statistics or related fields and 6+ years of academic / industry experience or PhD in computational biology bioinformatics statistics or related fields and 4 + years of academic / industry experience Preferred Qualifications Ph.D. in computational biology bioinformatics statistics or related fields. At least 4 years of industry experience or equivalent. Strong experience with data generated by one or more -omics or molecular assays is required (e.g. Next-Generation Sequencing scRNAseq spatial transcriptomics high parametric flow cytometry and in vitro immune function assays). Strong experience in the use of a high-level programming language such as R or Python for complex data analysis and reproducible research practices. Understanding of disease biology in oncology or immuno-oncology is preferred. The ability to evaluate and apply machine ML/AI methods is preferred. Ability to work both independently and collaboratively and to handle several concurrent fast-paced projects. Strong problem-solving and collaboration skills and rigorous and creative thinking. Excellent communication data presentation and visualization skills. Capable of establishing strong working relationships across the organization. #QLR If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work Life-changing Careers With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture promoting diversity in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role which the Company deems critical to collaboration innovation productivity employee well-being and engagement and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
