Job Description:
HOW MIGHT YOU DEFY IMAGINATION?
Do more with the knowledge you’re working hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Through this program, you will acquire the valuable hands-on skills and foundational experience to become the professional you are meant to be in your chosen field.
Grad Intern – R&D (Computational Chemistry)
Live
This could be your everyday
Let’s do this. Let’s change the world. During this program, you will develop machine learning-based tools for efficient conformational sampling of both small molecules and protein-ligand complexes. You will also have the opportunity to apply the tools you develop to drive drug discovery projects, by providing fast and accurate estimates of protein-ligand binding free energies. These tools will play an important role in guiding small molecule discovery and will be developed with mentorship from computational/medicinal chemists, data scientists, and machine learning engineers. The primary responsibilities of this role include:
Understand and build upon an existing python package for conformational sampling using normalizing flows Develop new capabilities to include multiple entities in the conformational search process using internal coordinate mapping Further improve sampling efficiency using attention mechanism or other techniques Develop techniques to estimate or rank protein-ligand binding affinities based on the generated conformational ensembles Hold regular result sharing presentations and discussion with other members of the team
Win
Here’s what it takes to Win
We are all different, yet we all use our unique contributions to serve patients. The intellectually curious and creative individual we seek is a next generation computational chemist with these qualifications:
Basic Qualifications
Amgen requires that all individuals applying for a grad internship or a co-op assignment at Amgen must meet the following criteria:
18 years or older Graduated with a Bachelor’s degree from an accredited college or university with a 3.0 minimum GPA or equivalent Currently enrolled in an MBA program for an MBA internship OR a Master’s program for a Master’s internship OR a PharmD program for a PharmD internship OR Ph.D. for a PhD internship from an accredited college or university and completion of the first year of MBA OR Master’s OR Pharm D OR Ph.D. program before the internship starts Enrolled in an accredited college or university following the potential internship or co-op assignment Must not be employed at the time the internship starts Student must be located in the United States for the duration of the internship
Preferred Qualifications
Degree concentration(s) in Computational Chemistry, Computational Physics, Applied Mathematics, Computational Biology, Bioinformatics, Biomedical Engineering, Computer Science, or a similarly quantitative discipline. Experience in machine learning algorithm development and a basic understanding of molecular dynamics/statistical mechanics principles Familiarity with molecular dynamics simulation software (Desmond, AMBER, GROMACS, OpenMM, or others) Familiarity with Python and data science/machine learning tools (scikit-learn, TensorFlow, PyTorch, or others)
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth in addition to their well-being.
The base pay range for this opportunity in the U.S. is $30-$40 per hour
Build a network of colleagues that will endure and grow throughout your time with us and beyond. Bring your authentic self to the table and become the professional you’re inspired to be through accepting a culture that values the diversity of thought and experience and will flex to your strengths and possibilities. Participate in executive and social networking events, as well as community volunteer projects.
Apply now
for an internship/co-op that defies imagination
If you feel like you're part of something bigger, it's because you are. Join us.
careers.amgen.com Please search for Keyword R-153983
Join Us
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancers, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. |
