Organisation Name: Johnson & Johnson Family of Companies
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Title: Scientist/Senior Scientist, Computational Chemistry Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist in Computational Chemistry, located in Beerse near Antwerp, Belgium. At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com/ for more information. We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it. Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer. Janssen Research & Development, LLC, is seeking a highly skilled and motivated computational chemist for the position of Scientist or Senior Scientist, Computational Chemistry, at our main European research center in Beerse, Belgium. The Scientist will use computational methods in small molecule drug discovery projects in close partnership with chemistry and therapeutic areas. We have invested in exploring molecular dynamics and free energy calculations both internally and via collaborations and a key aspect of this role will be to apply and test the new science in on-going projects. We also seek efficient implementation of technically difficult protocols via python notebooks or similar platforms. Therefore we are looking for good technical background and simulation expertise. Responsibilities of the Scientist will include: As a collabartor in drug discovery projects, develop and execute clear computational strategies to design complex molecules particularly using state of the art simulation approaches. Work in close collaboration with expert groups in AI/ML and simulation fields to implement novel computational approaches in an efficient way to aid small molecule drug discovery Participate in shaping and implementing structure-based strategies that support drug discovery at Janssen, including advanced molecular dynamics and free energy methods. Develop protocols suitable for non-expert colleagues in the computational group Play a leading role in collaborations with industry and academic partners and help the integration of new science to internal project applications Ensure optimal interaction/communication with project teams, deliver impact from computational methods, and provide updates on project status to discovery leadership Qualifications REQUIREMENTS: A PhD in computational chemistry or a related field with 1-2 years of experience applying computational chemistry in a drug discovery setting is preferred Expertise in applying advanced structure-based methods such as molecular dynamics or free energy methods Postdoctoral experience and/or experience in the biopharmaceutical industry is preferred Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives are required Demonstrated influence, negotiation, and conflict resolution skills, including the ability to succeed within a matrix environment are required Strong track record of scientific contributions including peer reviewed first-author publications Expertise with open-source or other academic standard simulation packages as well as demonstratable technical skils in scripting, python and/or equivalent language A good understanding of chemistry and small molecule/protein interactions as relevant in drug discovery Up to 10% travel both domestically and internationally is required
