Research Prime

Computational Scientist

Organisation Name: MOMA Therapeutics
Organisation Type:
City:
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Country: United States

Job Description:

MOMA Therapeutics is looking for a Computational Scientist

Imagine joining a company where you….

  • Will be part of an experienced and resilient team that is collectively unstoppable, trusts one another, and selflessly collaborates
  • Will work with incredible humans who are committed to the discovery of transformative medicines for patients
  • Are needed… because patients are counting on you

About MOMA Therapeutics

At MOMA Therapeutics, we are motivated by a single common goal, to discover and develop innovative new medicines for patients through our singular focus: the therapeutic targeting of molecular machines.

About the role…

We are looking for a computational scientist who can incorporate your knowledge of computational biophysics and data analytics and apply it to drug discovery. You will develop cutting edge physics-based computational methods to investigate dynamic proteins while deploying robust computational workflows to the drug discovery team. Through this role, you will be exposed to all stages of drug discovery and sharpen your skills in computational chemistry and data science.

In this role you will...

  • Develop and deploy computational methods and workflows to study conformationally flexible proteins, identify novel binding sites, and rationalize ligand selectivity.
  • Implement and apply computational chemistry, molecular design, and data analysis workflows to accelerate MOMA’s molecule design cycle. Interact closely with data engineers, medicinal chemists, and biologists to validate computational workflows and impact drug discovery programs.
  • Develop scalable and secure data infrastructure supporting data engineering and data science workflows – convert research into production processes.
  • Work collaboratively across diverse functions to achieve corporate goals.

About you:

  • You have a PhD in physics, computational chemistry/biophysics, computer science or related field.
  • You have a strong understanding of computational biophysical approaches, e.g. molecular dynamics, enhanced sampling methods, free energy calculation and quantum mechanics. Extensive experience with one or multiple simulation packages such as AMBER, GROMACS, OpenMM.
  • You are proficient in Python and its data science ecosystem, have interacted with databases, flat files, and APIs for data sources, and have gone from concept and notebook to production deployment.
  • You have experience working in a cloud environment (AWS), containerization (Docker), distributed compute (Dask, Nextflow, SLURM) and discernment on appropriate utilizations of such services
  • You enjoy the journey of building and implementing process as much as the science. 
  • You work hard, are kind to others, and enjoy being a part of a collaborative team that gets stuff done
  • Preferably, you have experience in supporting drug discovery programs, analyzing and virtual screening of large chemical library
  • You would consider yourself a team player who listens effectively, invites feedback, and participates in active discussion 
  • You work hard, you are kind to others, and you enjoy being a part of a kick-ass collaborative team that gets stuff done 
  • You like to build new things and bring your creativity to work with you 
  • You enjoy being in an environment where data drives the direction of the science 

 

MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

TO ALL AGENCIES: Please, no phone calls or emails to any employee of MOMA about our openings. All resumes submitted by search firms/employment agencies to any employee at MOMA via email, the internet or in any form and/or method will be deemed the sole property of MOMA, unless such search firms/employment agencies were engaged by MOMA for this position and a valid agreement with MOMA is in place. In the event a candidate who was submitted outside of the MOMA agency engagement process is hired, no fee or payment of any kind will be paid.


Posting Date: Feb 08, 2023
Closing Date:
Organisation Website/Careers Page: https://boards.greenhouse.io/momatherapeutics/jobs/4792376004


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