Research Prime

Process Science Associate - Computational Sciences (temp)

Organisation Name: Regeneron
Organisation Type:
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Country: Ireland

Job Description:

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our outstanding ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories.

Our medicines and pipeline are crafted to help patients with eye disease, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, infectious diseases, pain and rare diseases. Our mission is to use the power of science to bring new medicines to our patients.

Process Sciences is a technical services department that deals with a range of scientific, technical, engineering and mathematical needs from the laboratory to the manufacturing floor. Process Sciences support the following areas Upstream Sciences, Downstream Sciences, Analytical Technologies, IPC lifecycle, Data Analytics, Manufacturing Support, Process Validation and Process Solutions.

Summary:

Supports the Process Sciences department to create bioprocess models using mechanistic modelling and other techniques to generate technical solutions across the bio manufacturing platform.

Based at the Raheen site, the Associate Process Specialist will work with mathematicians, engineers and scientists.  This role will focus on the use of advanced chemical and biochemical engineering modelling principles within manufacturing.  

Essential Duties and Responsibilities include, but are not limited to, the following:

  • Source and assess appropriate technical data from manufacturing and other equipment across the network.
  • Build and maintain mathematical models of biochemical processes including cell kinetics modelling and liquid chromatography modelling, among others.
  • Understand and apply mathematical modelling principles related to Michaelis–Menten kinetics, transport-reaction models, fluid flow in porous media and mass transfer models.
  • Work with the Computational Fluid Dynamics team to advise on models that are representative of process and equipment.
  • Work collaboratively with mathematicians, engineers and scientists across the network.
  • Prepare presentations summarizing project outcomes for management, supporting documentation and reports.
  • Work effectively and efficiently in a team-oriented environment to ensure maximum and high-quality output.
  • Conduct extensive literature searches and reviews to identify industry-leading techniques for model development and validation.

Education and Experience:

BSc/BEng in Mathematical Sciences, Mathematical Modelling, Chemical and/or Biochemical Engineering, or Physics. Some experience working with MATLAB, Python, GoSilico and/or CADET software and knowledge of discretization schemes, numerical solutions of partial differential equations and model suitability preferred but not essential. Level will be commensurate with experience and education.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

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Posting Date: Sep 06, 2022
Closing Date:
Organisation Website/Careers Page: https://careers.regeneron.com/job/REGEA0026R12424EXTERNALENUS/Process-Science-Associate-Computational-Sciences-temp


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